Postdoctoral position (group led by Dr. Mari, Aarhus University, Denmark)

The Department of Biomedicine at the Faculty of Health at Aarhus University invites applications for a position as postdoctoral fellow within area of autophagy as per 1st November 2024 or as soon as possible thereafter. The position is a fixed-term full-time position for 2 years initially.

About the research project

Autophagy is a catabolic process highly conserved among eukaryotes, which is involved in the degradation of long-lived proteins, aberrant complexes and aggregates, dysfunctional and superfluous organelles, and intracellular pathogens. Structures targeted to destruction, including intracellular organelles, are sequestered by double-membrane vesicles called autophagosomes and delivered to lysosomes for turnover. The key actors of autophagy are the autophagy-related (ATG) proteins. Autophagy can be highly selective and target specific unwanted structures using the so-called selective autophagy receptors (SARs) and various adaptor proteins.

The overall aim of the project is to understand the selective and bulk autophagy mechanisms at the ultrastructural levels by studying these mechanisms in healthy or neurodegenerative conditions.

Start: November 1st 2024 (or as soon as possible thereafter)