One postdoctoral and two PhD student positions in Switzerland
and the Netherlands
The laboratories of Prof. Joern Dengjel (Department of Biology, University of Fribourg, Switzerland), Dr. Mattia Zampieri (Institute of Molecular Systems Biology, ETH Zurich, Switzerland) and Prof. Fulvio Reggiori (Department of Biomedical Sciences of Cells and SystemsUniversity Medical Center Groningen, The Netherlands) are looking for excellent and highly motivated candidates to join their groups for the realization of a multidisciplinary and collaborative project, aimed at understanding the contribution of autophagy to cell physiology. The study will be initially performed in yeast Saccharomyces cerevisiae before we will transfer key principles to cancer cells. The project is supported by the Sinergia program of the Swiss National Science Foundation (SNSF).
Specific requirements:
PhD position in the Dengjel lab: Solid background in protein biochemistry or cell biology. Experience with mass spectrometry is a plus, but not absolutely necessary.
Postdoctoral position in the Zampieri lab: Candidates should have a PhD with a strong background in physics and/or mathematical modeling. Experience in programming, model fitting and statistical analysis is expected. Good communication skills in oral and written English are essential.
PhD position in the Reggiori lab: Solid background in cell biological and/or biochemical techniques. Previous work with yeast and fluorescence microscopy is a plus, but not absolutely necessary.
If interested in one of these positions, please contact the concerned person by email (Joern Dengjel, joern.dengjel@unifr.ch; Mattia Zampieri, zampieri@imsb.biol.ethz.ch; Fulvio Reggiori, f.m.reggiori@umcg.nl), including in the message a letter of motivation, a CV and the contact information of 2-3 references.
Postdoc position – Regenerative Medicine Center Utrecht
Profile
We are looking for an enthusiastic, highly motivated candidate with a strong interest in a molecular understanding of biology. We are especially interested in applicants that are excited to work in a collaborative and multidisciplinary environment and have solid background in cell and molecular biology.
Project
The project aims to characterize the molecular mechanisms underlying the anti-inflammatory and regenerative properties of MSC-derived extracellular vesicles (MSC-EVs) in cartilage repair. The research is a follow up of our work showing that MSC-EVs are an important component of MSC paracrine signalling and have a major contribution to cartilage regeneration and inhibition of inflammatory responses in osteoarthritic chondrocytes.
You will be working with the variety of techniques including: differential centrifugation and sucrose gradient, size exclusion chromatography, Western blotting, flow cytometry, cell culture, confocal microscopy, electron microscopy, nanoparticle tracking analysis, cutting edge cloning techniques, lentiviral transductions, making transgenic cell lines, co-culture, siRNA knock down and Crispr-Cas9 technology. The project will also make use of the unique material from osteoarthritic patients.
Organization
You will be working at the Regenerative Medicine Center in Utrecht, which offers an international, very dynamic and stimulating work environment. The RMCU is an inter-faculty initiative with scientists from medicine and veterinary medicine gathered together. This provides a unique collaborative setting for regenerative medicine projects. The RMCU houses the world-class equipment and is located in the scientific campus of the Utrecht University with the access to a large number of facilities. Utrecht is beautiful city located in the center of the Netherlands, in close proximity of Amsterdam and its international airport.
Application deadline: 28 February 2019
Application process: Please send one PDF document containing a cover letter with your motivations, a very concise summary of previous research activities, the curriculum vitae and the contact details for 3 referees to m.j.lorenowicz@umcutrecht.nl
Further information: For more information on the research focus of the group please check our website. For questions about the position, please send an email to m.j.lorenowicz@umcutrecht.nl
15 PhD positions are available in the field of Autophagy around Europe
Positions in Finland, France, Germany, Israel, Netherlands, Norway, Spain, and United Kingdom
DRIVE (Driving next generation autophagy researchers towards translation) is a Marie Skłodowska-Curie Action (MSCA), Innovative Training Network (ITN) H2020-MSCA-ITN-2017, funded by the European Commission under Grant Agreement n. 765912.
Eligibility (who can apply): Early-Stage Researchers (ESRs).
Application: eligible candidates should fill in the application form and upload a cover letter stating their motivation and research interests, an updated CV with the dates of relevant diplomas (day, month and year), and the contact information of 2 referee persons.
Applicants should apply to their preferred research team within DRIVE’s network (click here for details), but they can indicate a secondary and tertiary preference in their application.